fMRI Study Shows Specific Visual Training Effect on Brain Activity

Released on: August 19, 2008, 1:20 am

Press Release Author: NovaVision AG

Industry: Healthcare

Press Release Summary: New Functional Magnetic Resonance Images Demonstrates Brain
Activity Supporting Vision Restoration Therapy's Ability to Enhance Vision in Stroke
Patients

Press Release Body: (New York / Magdeburg) - Columbia University Medical Center
researchers have demonstrated, using functional magnetic resonance imaging (fMRI),
that brain activity was increased in stroke survivors who underwent Vision
Restoration Therapy (VRT), a rehabilitative treatment that helps these patients
recover lost vision. The data have been published in the journal Neurorehabilitation
and Neural Repair on April 1, 2008.

Researchers, led by Randolph S. Marshall, M.D., M.S., associate professor of
clinical neurology and acting director, Division of Stroke and Critical Care at
Columbia University College of Physicians and Surgeons, examined the fMRIs of six
patients aged 35-77 with vision loss on the same side of both eyes (homonymous
hemianopia) caused by stroke. The therapy is based on visual stimulation, which the
patient performs daily at home on a dedicated computer device. The fMRI data showed
increased activity in visual processing areas of the brain as patients learned to
detect stimuli in the borderzone between the seeing and non-seeing fields. This
enhanced activity was identified one month after beginning treatment and suggests
that the brain is responding accordingly.

"This study is encouraging because the fMRI technique allowed us to see and compare
the activity levels in specific regions of the brain before and during Vision
Restoration Therapy. After examining the images, the increased activity levels
demonstrate progress associated with the treatment," said Dr. Marshall. "Based on
these initial results, we will continue to investigate the relationship between the
imaging findings and the degree to which vision is recovered."

The findings underscore the growing scientific evidence validating Vision
Restoration Therapy. For stroke survivors with impaired vision, these data further
show that VRT may help them regain lost sight - and ultimately help them reclaim
their independence.

Developed in Germany VRT is approved by the U.S. Food and Drug Administration to
treat vision problems in people who have been left partially blind due to stroke or
brain trauma. Customized treatment is created from a comprehensive diagnostics that
map the seeing and non-seeing areas of vision. Patients perform the therapy daily at
home for six to seven months, gradually improving their vision through the repeated
detection of light stimuli directed at the border between the seeing and blind areas
of the visual field.

Vision Restoration Therapy is currently offered in U.K. in Bristol by Janice Juul,
an optometrist with a lot of neurological experience (70 Alma Road, BS8 2DJ Clifton
Bristol).

For more information please visit www.vision-impairment.com or call
+49(0)391-6360050.

Web Site: http://www.vision-impairment.com

Contact Details: NovaVision AG
Klausenerstr. 12
39112 Magdeburg
Germany
Tel: +49 (0)391-6360050
Fax: +49 (0)391-6360070
info@novavision.de
www.vision-impairment.com

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